Abstract:
Diabetes Mellitus (DM) and Thyroid D
ysfunction
(TD)
are the two most common
endocrinopathies seen in general population.
T
ype 2 d
iabetes
m
ellitus(T2DM) is
commonly associated with altered thyroid
function.
The aim of
the
research i
s
to
evaluate
TD
in patients w
ith
T
2DM
attending E
ndocrinology C
linic of
UsmanuDanfodiyo
University
Teaching Hospital
,
Sokoto.
Blood s
ample
s were
collected
f
rom
80
T
ype 2
diabetic
patients
a
nd 80 non diabetic (control) and
analyze
fo
r fasting blood s
ugar (
FB
S
)
, g
ly
cated
he
moglobin
(HbA
1c
)
,
t
h
yroid
stimulating
h
ormone (TS
H)
,
t
ri
i
odothyrorine (T3),
t
hyroxin (T4
)
,
cholesterol,
t
riglycerides (T
G
)
,
high density l
ipoprotein (
H
DL
-
C
)and low
density
l
ipoproteins
(LDL
-
C)
.
The level
s
,
of FBS, HbA1
c
,
Cholesterol, TG
and LDL
-
C
were
observ
ed
to be
signif
icantly high and
the
level of H
DL
-
C
was
significantly
low
in diabetics as compared to
control(
non dia
betic patients
)
.
The level
s
of T3
and T4
were
significantly low while the level of TSH was signif
icantly high in
T
ype 2 diabetic
s
a
s compared to
non diabetic
s
.
Pearson correlation shows a
very strong positive relationship between FBS and HbA1c and weak
positive
relationship between
these
s
ugar
s
and Thyroid hormones
(TSH,T3
,and
T4
)
.
Thyroid
dysfunction
may
complicates metabolic con
t
r
o
l in diabetes melli
tus
(DM).It is
therefore patients
to recognize and
where necessary
treat thyroid
dysfunction in order to stabilize metabolic control.
