Hypoglycemic and hypolipidaemic effects of aqueous extract of Arachis hypogea in normal and Alloxan-induced diabetic rats

Abstract

The hypoglycemic and hypolipidaernic effect of aqueous extract of Arachis hypogea was investigated in normal and alloxan-induced diabetic rats. The extract caused a significant (P < 0.05) decrease of fasting blood glucose of both normal and alloxan-induced diabetic rats from 102.60 ± 1.65 mgldl to 88.79 ± 0.94 mgldl for normal and 189.0 ± 30.79 mgldl to 107.55 ± 1.54 mgldl for alloxan-induced diabetic rats. The extract also caused a significant (P < 0.05) decrease in serum triglyceride, total cholesterol, HDL-cholesterol and LDL-cholesterol in both normal and alloxan-induced diabetic rats.