Effects of Anthraquinone Glycosides and Aqueous Ethanol Extracts of Ficus sycomorus L. (Moraceae) on Rat Liver and Kidney Functions

Hassan, S.W; Lawal, M; Muhammad, B.Y; Umar, R.A; Bilbis, L.S; Saidu, Y

dc.contributor.author	Hassan, S.W
dc.contributor.author	Lawal, M
dc.contributor.author	Muhammad, B.Y
dc.contributor.author	Umar, R.A
dc.contributor.author	Bilbis, L.S
dc.contributor.author	Saidu, Y
dc.date.accessioned	2017-10-30T16:59:35Z
dc.date.available	2017-10-30T16:59:35Z
dc.date.issued	2007
dc.identifier.issn	1815-.9923
dc.identifier.uri	http://hdl.handle.net/123456789/247
dc.description.abstract	The anthraquinone glycosides composition and toxicity studies of isolated anthraquinone glycosides and aqueous ethanol stern bark extracts of Ficus sycomorus on rat liver and kidney functions were conducted. The yield of anthraquinone glycosides in 40 g powdered stem bark extract was 16.0% (w/v). Liver and renal indices were significantly (p<0.05) changed at higher doses of617.86, 988.57 (anthraqiunone glycosides), 767.80 and 1228.60 mg kg-' body weight (aqueous ethanol extract). Dose dependant decrease in weight (p<0.05) was observed in the rats administered higher doses of the aqueous ethanol and anthraquinone glycosides extracts. The results suggest that extracts of Ficus sycomorus cause adverse effects to liver and kidney at higher doses.	en_US
dc.language.iso	en	en_US
dc.publisher	Asian Journal of Biochemistry	en_US
dc.subject	Department of Biochemistry	en_US
dc.title	Effects of Anthraquinone Glycosides and Aqueous Ethanol Extracts of Ficus sycomorus L. (Moraceae) on Rat Liver and Kidney Functions	en_US
dc.type	Article	en_US