MECHANISM FOR THE ADSORPTION OF MUCIN ON HYDROXYAPATITE

Abstract

The adsorptive ability of mUCIn onto hydroxyapatite was evaluated based on its adsorptive amount and adsorptive strength. The adsorptive amount was determined by measuring the amount of mucin adsorbed onto hydroxyapatite while adsorptive strength was determined by measuring the amount of mucin remaining adsorbed after rinsing. I The amount of mucin adsorbed onto the substrates in all cases followed the order Sigma grade HAP> synthesized HAP> CHP and generally increased with increase in the amount of adsorbent. More than 80% of mucin was adsorbed unto HAP with or without Ca 2 + ion pretreatment. The adsorption isotherm fitted the Langmuir model and electrostatic attraction mechanism is proposed.