Abstract:
The
effects
of aqueous
leaf
extract
of
Cassia
siamea
on haematological
parameters
in albino
rats
were
investigated.
Twenty
(20)
rats
weighing
between
100
and
200g
were
divided
into
four
groups
(A, B, C and
D) of five
rats
each.
Groups
B, C and
D
were
administered
the
extract
orally
at a daily
dose
ofO.5g1kg,
1.0g/kg
and
l.Sg/kg
body
weight
respec-
tively
for twenty-eight
(28)
days,
while
group
A (control)
received
saline.
Blood
parameters
were
determined
prior
to
extract
administration
and
at every
7 days
for 28 days.
Haematological
analysis
of blood
indicated
significant
decrease
(P<O.OS)
in red
blood
cells
and
hemoglobin
concentration
at aU treatment
doses
while,
white
blood
ceJls
and
platelets
count
showed
significant
increase
(P<O.OS).
These
alterations
of blood
parameter
noticed
are
of clinical
consequence.
