Abstract:
Thc
toxicological
effects
of the aqueous
leaf extract
of
Cassia
occideutalis
Linn were
in
rats.
Acute
toxicitv
study
was
conducted
following
intraperitoneal
administration of graded
doses
of the
plant
extract.
LD of cassia
occidentalis
extract
was
found
to be
1680mg/kg body weight.
Mortality occurred
in rats
given the
extract
at high
doses
of 1200,
1800,
2600
and 3200mg/kg
and
appear to be
dose
dependent.
Phytochemical
analysis
of the
aqueous
extract
of cassia
occidentalis
leaf
indicated
that it
contained
tannins,
anthraquinoncs.
sterols, glycosides,
saponin,
and
alkaloids.