SE.RUM LIPID PRO,FILE O'F' DIABETIC PATIENTS FROM BIRNIN KEBBI - NIGERIA

Abstract

Serum lipid profiles were estimated in 30 type 1 and 40 type 2 diabetes patients of the out patien tdinicoftheSirYahayaMeIICIO'I"iaIrHaspiJtaBl,itrRin-Kebbi,KebbiState, Nigeria. Thedata on thepatients wereanalysed with reference to 45apparently healthycontrollsubjects with normalglycaemicstatus.Botb,type1.andtJlpe2maleshadsignificantly(P<O.05)lowerlevel ofhigh-density lipoprotein cholesterol (HDL-C) than the control. Total c/;"ole~erol (rC) level of type 1 males and TC,and low-density lipoprotein cholesterol (LDL.-C) level of the type 2 mafesweresignificantly(P<O~05 ],higb,erthan therespective controis. The·t.ype2femaleshad higherleve/sofTCrLDL-C,andtriacylglycero/(TAG) than thecontrolfemales. TlleTAGoftype2 femalesissignificantly(P<O.05 )higherthan thatoftype 1females. ThelevelsofTC andLDL-C were significantly (P<0.05) higher for the type 2 females than their male counterparts. Twenty three percent, 200/0, and 270/0 of the type 1 patients had hypercholesterolaemia, hypertriglyceridaemia, andcombined hyper-lipidaemia respectively. In the type 2 patients however 300/0, 350/0, and 450/0 had hypercholesterolaemia, hypertriglyceridaemia, and combined hyperlipidaemia respectively. Compared to the pooled values, the prevalence decreasedtnthemales tc swo,230/o,and27% respectively. Dyslipidaemia ismorecommon in female diabetics than in their male counterparts. These observations revealed that the occurrence of lipid abnormalities in Kebbi diabetics, especially the type 2 patients, is substantiaIandmayacceleratethe riskofatherosclerosis inthe patients