Preliminary studies of antidote to snake venom from plant based materials

Bilbis, L.S; Muazu, A.G; Abubakar, M.G

dc.contributor.author	Bilbis, L.S
dc.contributor.author	Muazu, A.G
dc.contributor.author	Abubakar, M.G
dc.date.accessioned	2017-10-31T09:46:23Z
dc.date.available	2017-10-31T09:46:23Z
dc.date.issued	1995
dc.identifier.issn	0189·4757
dc.identifier.uri	http://hdl.handle.net/123456789/266
dc.description.abstract	The ability of the plant extract "Danya" (Sc/erocarya birrea) to neutralize the necrotic and haemorrhagic effect of Naja naja and Naja nigricol/is venom was investigated. The plant extract of various doses were pre-incubated with the venoms for 30 minutes at room temperature prior to intramuscular administration to rats. Cold extract of this plant completely neutralized the necrotic and haemorrhagic effect of the two venoms. Cold extract of this plant also exhibited a heat stable anticoagulant property. This anticoagulant property was found to reside in the chloroform fraction of the extract which could be responsible for the neutralization of necrotic and haemorrhagic effect of the venoms. The identity of this neutralization factor and/or the anticoagulant substance(s) is currently under investigation.	en_US
dc.language.iso	en	en_US
dc.publisher	Nigerian Journal of Biochemistry and Molecular Biology	en_US
dc.subject	Department of Biochemistry	en_US
dc.title	Preliminary studies of antidote to snake venom from plant based materials	en_US
dc.type	Article	en_US